Andrew once reportedly made a rude comment about Princess Kate, it has been claimed (Image: Karwai Tang/WireImage)

Andrew’s relationship with Prince William is reportedly strained due to the scandals surrounding the former Duke of York and his association with convicted sex offender Jeffrey Epstein. However, the Prince of Wales may also be at loggerheads with Andrew, who is being stripped of his titles by King Charles, following a reported “rude” remark.

Andrew, 65, is claimed to have once made “rude” remarks about William’s wife, Princess Kate, that sent the heir to the throne “over the edge”. This claim was made in the royal book ‘Entitled: The Rise and Fall of the Yorks’ by Andrew Lownie, who researched the disgraced royal for a number of years. In the book, Lownie claimed a source told him that Andrew and William had not been on good terms for some time.

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As reported by The Mirror, the source claimed that tensions between uncle and nephew began when Andrew first started tarnishing the reputation of the monarchy. The former Duke has denied any wrongdoing and rejected allegations made against him by the late Virginia Giuffre.

The relationship between the two men is then believed to have worsened when Andrew, formally The Duke of York, said something disrespectful about Princess Kate.

Although it is not known exactly what Andrew said, the comment was believed to have enraged William and put a dent in the relationship between the prince and his uncle.

It is also believed to have been one of the reasons why William was very involved in encouraging his father to strip Andrew of his royal titles and evict him from his 30-room Royal Lodge home – something that King Charles announced would happen on Thursday night.

Andrew and Prince William reportedly do not get on (Image: Max Mumby/Indigo/Getty Images)

Neither Prince William or Andrew have addressed the claim regarding the alleged comment about Kate.

They have also not publicly commented on whether or not they get on, with William sharing a good relationship with Andrew’s daughters Princess Eugenie and Princess Beatrice, who are his cousins.

However, after standing side by side at the Duchess of Kent’s funeral last month, royal fans thought the tension between William and Andrew was clear to see, with William visibly trying to ignore Andrew when the former prince tried to speak to him.

It was widely reported that Prince William, who is first-in-line to the throne, was “furious” at the way Andrew tried to engage with him in front of the cameras, with the prince reportedly feeling “ambushed”.